Research Output 1998 2017

  • 917 Citations
  • 18 h-Index
  • 91 Article
  • 1 Letter
  • 1 Review article
2017
Cytochrome P-450 CYP2D6
Genetic Polymorphisms
Genome
Genes
Gene Duplication

Metabolomic-guided discovery of Alzheimer's disease biomarkers from body fluid

Enche Ady, C. N. A., Lim, S. M., Teh, L. K., Salleh, M. Z., Chin, A. V., Tan, M. P., Poi, P. J. H., Kamaruzzaman, S. B., Abdul Majeed, A. B. & Ramasamy, K. 2017 (Accepted/In press) In : Journal of Neuroscience Research.

Research output: Research - peer-reviewArticle

Metabolomics
Body Fluids
Alzheimer Disease
Biomarkers
Disease Management
1 Citations
Flavonoids
Anti-Inflammatory Agents
Antioxidants
ethyl acetate
Stomach

Synthesis of azomethines derived from cinnamaldehyde and vanillin: in vitro aetylcholinesterase inhibitory, antioxidant and insilico molecular docking studies

Chigurupati, S., Selvaraj, M., Mani, V., Mohammad, J. I., Selvarajan, K. K., Akhtar, S. S., Marikannan, M., Raj, S., Teh, L. K. & Salleh, M. Z. Nov 10 2017 (Accepted/In press) In : Medicinal Chemistry Research. p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Antioxidants
cinnamic aldehyde
vanillin
In Vitro Techniques
Scavenging
2016

Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models

Zakaria, Z. A., Jaios, E. S., Omar, M. H., Abd. Rahman, S., Hamid, S. S. A., Ching, S. M., Teh, L. K., Salleh, M. Z., Deny, S. & Taher, M. Nov 29 2016 In : BMC Complementary and Alternative Medicine. 16, 1, 488

Research output: Research - peer-reviewArticle

TRPV Cation Channels
Triterpenes
Palmitic Acid
Phytochemicals
Complex Mixtures
1 Citations

Antinociceptive effect of semi-purified petroleum ether partition of muntingia calabura leaves

Zakaria, Z. A., Mohd Sani, M. H., Kadir, A. A., Kek, T. L. & Salleh, M. Z. 2016 In : Brazilian Journal of Pharmacognosy. 26, 4, p. 408-419 12 p.

Research output: Research - peer-reviewArticle

naphtha
Cyclic GMP
Bradykinin
Opioid Analgesics
Hot Temperature
1 Citations

Assessment of risk and sero-prevalence of Helicobacter pylori colonization among remote Orang Asli tribes in Peninsula Malaysia

Thevakumar, K., Chandren, J. R., Perez-Perez, G. I., Chua, E. G., Teh, L. K., Salleh, M. Z., Tan, J. A. M. A., Leow, A. H. R., Goh, K. L., Tay, A. C. Y., Marshall, B. J., Vadivelu, J., Loke, M. F. & Wong, L. P. Jul 1 2016 In : PLoS One. 11, 7, e0159830

Research output: Research - peer-reviewArticle

tribal peoples
Helicobacter pylori
seroprevalence
Malaysia
risk assessment
1 Citations
Pharmacology
corrigendum
1 Citations

Coupling genotyping and computational modeling in prediction of antiepileptic drugs that cause Stevens Johnson syndrome and toxic epidermal Necrolysis for carrier of HLA-B*15: 02

Teh, L. K., Selvaraj, M., Bannur, Z., Ismail, M. I. M., Rafia, M. H., Law, W. C., Sapuan, S., Puvanarajah, S., Ali, P. S. S. & Salleh, M. Z. Mar 21 2016 In : Journal of Pharmacy and Pharmaceutical Sciences. 19, 1, p. 147-160 14 p.

Research output: Research - peer-reviewArticle

Stevens-Johnson Syndrome
HLA-B Antigens
Anticonvulsants
Primidone
Precision Medicine

Detection of CYP2C19 genetic variants in Malaysian Orang Asli from massively parallel sequencing data

Ang, G. Y., Yu, C. Y., Subramaniam, V., Khalid, M. I. H. A., Aziz, T. A. T. A., James, R. J., Ahmad, A., Rahman, T. A., Nor, F. M., Ismail, A. I., Isa, K. M., Salleh, H., Teh, L. K. & Salleh, M. Z. Oct 1 2016 In : PLoS One. 11, 10, e0164169

Research output: Research - peer-reviewArticle

High-Throughput Nucleotide Sequencing
Alleles
Cytochrome P-450 CYP2C19
alleles
high-throughput nucleotide sequencing
1 Citations

Gastroprotective activity of chloroform extract of Muntingia calabura and Melastoma malabathricum leaves

Zakaria, Z. A., Zainol, A. S. N., Sahmat, A., Salleh, N. I., Hizami, A., Mahmood, N. D., Nasir, N., Mamat, S. S., Kamisan, F. H., Mohtarrudin, N., Abdul Hamid, S. S., Tohid, S. F., Teh, L. K. & Salleh, M. Z. May 3 2016 In : Pharmaceutical Biology. 54, 5, p. 812-826 15 p.

Research output: Research - peer-reviewArticle

Chloroform
Stomach Ulcer
Ethanol
Antioxidants
Triterpenes

Genetic epidemiology of pharmacogenetic variants in South East Asian Malays using whole-genome sequences

Sivadas, A., Salleh, M. Z., Teh, L. K. & Scaria, V. May 31 2016 (Accepted/In press) In : Pharmacogenomics Journal.

Research output: Research - peer-reviewArticle

Molecular Epidemiology
Pharmacogenetics
Genome
Population
Pharmacogenomic Variants

Genome sequencing and annotation of multidrug resistant Mycobacterium tuberculosis (MDR-TB) PR10 strain

Halim, M. Z. A., Jaafar, M. M., Teh, L. K., Ismail, M. I., Lee, L. S., Ngeow, Y. F., Nor, N. M., Zainuddin, Z. F., Tang, T. H., Najimudin, M. N. M. & Salleh, M. Z. Mar 1 2016 In : Genomics Data. 7, p. 245-246 2 p.

Research output: Research - peer-reviewArticle

Multidrug-Resistant Tuberculosis
Nucleic Acid Databases
Mycobacterium tuberculosis
Genome
Genes

Genome Sequencing and Annotation of Mycobacterium tuberculosis PR08 strain

Jaafar, M. M., Halim, M. Z. A., Ismail, M. I., Shien, L. L., Kek, T. L., Fong, N. Y., Nor, N. M., Zainuddin, Z. F., Hock, T. T., Najimudin, M. N. M. & Salleh, M. Z. Mar 1 2016 In : Genomics Data. 7, p. 119-120 2 p.

Research output: Research - peer-reviewArticle

Mycobacterium tuberculosis
Genome
Genes
Nucleic Acid Databases
Cerebrospinal fluid
1 Citations

Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms

Zakaria, Z. A., Yahya, F., Mamat, S. S., Mahmood, N. D., Mohtarrudin, N., Taher, M., Hamid, S. S. A., Teh, L. K. & Salleh, M. Z. Jun 11 2016 In : BMC Complementary and Alternative Medicine. 16, 1, 175

Research output: Research - peer-reviewArticle

Bauhinia
Acetaminophen
Methanol
Antioxidants
Liver
7 Citations

Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies

Chigurupati, S., Selvaraj, M., Mani, V., Selvarajan, K. K., Mohammad, J. I., Kaveti, B., Bera, H., Palanimuthu, V. R., Teh, L. K. & Salleh, M. Z. Aug 1 2016 In : Bioorganic Chemistry. 67, p. 9-17 9 p.

Research output: Research - peer-reviewArticle

Cholinesterase Inhibitors
Derivatives
Acetylcholinesterase
Scavenging
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid

Increased risks of cardiovascular diseases and insulin resistance among the Orang Asli in Peninsular Malaysia

Tuan Abdul Aziz, T. A., Teh, L. K., Md Idris, M. H., Bannur, Z., Ashari, L. S., Ismail, A. I., Ahmad, A., Isa, K. M., Nor, F. M., Rahman, T. H. A., Shaari, S. A. B., Jan Mohamed, H. J., Mohamad, N. & Salleh, M. Z. Mar 24 2016 In : BMC Public Health. 16, 1, 284

Research output: Research - peer-reviewArticle

Disease Resistance
Malaysia
Insulin Resistance
Cardiovascular Diseases
Urban Population
7 Citations

Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura

Zakaria, Z. A., Balan, T., Azemi, A. K., Omar, M. H., Mohtarrudin, N., Ahmad, Z., Abdullah, M. N. H., Desa, M. N. M., Teh, L. K. & Salleh, M. Z. Feb 24 2016 In : BMC Complementary and Alternative Medicine. 16, 1, 78

Research output: Research - peer-reviewArticle

ethyl acetate
Nitric Oxide
Prostaglandins E
Stomach
Gallic Acid

Prevalence and risk factors of metabolic syndrome among an endangered tribal population in Malaysia using harmonized IDF criteria

Ashari, L. S., Mitra, A. K., Rahman, T. A., Mitra, A., Teh, L. K., Salleh, M. Z. & Jan Mohamed, H. J. B. Sep 1 2016 In : International Journal of Diabetes in Developing Countries. 36, 3, p. 352-358 7 p.

Research output: Research - peer-reviewArticle

Malaysia
Population
Surveys and Questionnaires
Waist Circumference
HDL Cholesterol

Systematic characterization and comparison of the CYP2C9 variability of the Orang Asli in Malaysia with 12 populations

Teh, L. K., Subramaniam, V., Tuan Abdu Aziz, T. A., Lee, L. S., Ismail, M. I., Yu, C. Y., Ang, G. Y., James Johari, R., Ismet, R. I., Sahak, N. S., Ahmad, A., Rahman, T. A., Nor @ Ghazali, F. M., Shaari, S. A., Omar, M., Ismail, A. I., Md. Isa, K., Salleh, H. & Salleh, M. Z. Aug 1 2016 In : Drug Metabolism and Pharmacokinetics. 31, 4, p. 304-313 10 p.

Research output: Research - peer-reviewArticle

Malaysia
Population
Cytochrome P-450 CYP2C9
Gene Frequency
HapMap Project
1 Citations

Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring

Farah Naquiah, M. Z., James, R. J., Suratman, S., Lee, L. S., Mohd Hafidz, M. I., Salleh, M. Z. & Teh, L. K. Aug 31 2016 In : Behavioral and Brain Functions. 12, 1, 23

Research output: Research - peer-reviewArticle

Heroin Dependence
Heroin
Aggression
Anxiety
Paternal Exposure
2015
1 Citations
Norepinephrine Plasma Membrane Transport Proteins
Serotonin Plasma Membrane Transport Proteins
Somatoform Disorders
Depression
Therapeutics
3 Citations
Lactobacillus casei
Probiotics
Obesity
probiotics
obesity
8 Citations

Isolating the metabolic pathways involved in the hepatoprotective effect of Muntingia calabura against CCl4-induced liver injury using LC/MS Q-TOF

Rofiee, M. S., Yusof, M. I. M., Abdul Hisam, E. E., Bannur, Z., Zakaria, Z. A., Somchit, M. N., Teh, L. K. & Salleh, M. Z. May 26 2015 In : Journal of Ethnopharmacology. 166, p. 109-118 10 p.

Research output: Research - peer-reviewArticle

Metabolomics
Metabolic Networks and Pathways
Liver
Wounds and Injuries
Body Water
3 Citations

Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Zakaria, Z. A., Balan, T., Mamat, S. S., Mohtarrudin, N., Kek, T. L. & Salleh, M. Z. Dec 12 2015 In : BMC Complementary and Alternative Medicine. 15, 1, 135

Research output: Research - peer-reviewArticle

Methanol
quercitrin
Gastric Juice
Xanthine Oxidase
Mucus
6 Citations

Mechanisms of α-Mangostin-Induced Antinociception in a Rodent Model

Mohd. Sani, M. H., Taher, M., Susanti, D., Kek, T. L., Salleh, M. Z. & Zakaria, Z. A. Jan 19 2015 In : Biological Research for Nursing. 17, 1, p. 68-77 10 p.

Research output: Research - peer-reviewArticle

Rodentia
mangostin
Arginine
Methylene Blue
Constriction

Nodamura virus B2 amino terminal domain sensitivity to small interfering RNA

Shaik Syed Ali, P., John, J., Selvaraj, M., Kek, T. L. & Salleh, M. Z. May 1 2015 In : Microbiology and Immunology. 59, 5, p. 299-304 6 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Viruses
Double-Stranded RNA
Circular Dichroism
RNA Interference
2 Citations

The genome sequence of Acinetobacter baumannii isolated from a septicemic patient in a local hospital in Malaysia

Izwan, I., Teh, L. K. & Salleh, M. Z. Dec 1 2015 In : Genomics Data. 6, p. 128-129 2 p.

Research output: Research - peer-reviewArticle

MDR Genes
Acinetobacter baumannii
Malaysia
Nucleic Acid Databases
Cross Infection
1 Citations

The Genome Sequence of a Type ST239 Methicillin-Resistant Staphylococcus aureus Isolate from a Malaysian Hospital

Lee, L. S., Teh, L. K., Zainuddin, Z. F. & Salleh, M. Z. Oct 30 2015 (Accepted/In press) In : Standards in Genomic Sciences.

Research output: Research - peer-reviewArticle

Methicillin-Resistant Staphylococcus aureus
Clone Cells
Genome
Local Anti-Infective Agents
Malaysia
1 Citations

The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin

Abdul Jalil, N. J., Bannur, Z., Derahman, A., Maskon, O., Darinah, N., Hamidi, H., Ali, O., Gunasekaran, . N. V., Rafizi, M., Azreen, N. I., Kek, T. L. & Salleh, M. Z. Sep 30 2015 In : Journal of Pharmacy and Pharmaceutical Sciences. 18, 3, p. 474-483 10 p.

Research output: Research - peer-reviewArticle

Cyclooxygenase 1
Aspirin
Cardiovascular Diseases
Cytochrome P-450 CYP2C9
Gastritis
2014
11 Citations

Antinociceptive activity of methanolic extract of Muntingia calabura leaves: Further elucidation of the possible mechanisms

Zakaria, Z. A., Sani, M. H. M., Cheema, M. S., Kader, A. A., Kek, T. L. & Salleh, M. Z. Feb 20 2014 In : BMC Complementary and Alternative Medicine. 14, 63

Research output: Research - peer-reviewArticle

Methanol
Opioid Analgesics
Phytochemicals
Bradykinin
Flavonoids
4 Citations

Complete mitochondrial genome of Malaysian Mahseer (Tor tambroides)

Norfatimah, M. Y., Teh, L. K., Salleh, M. Z., Mat Isa, M. N. & SitiAzizah, M. N. Sep 15 2014 In : Gene. 548, 2, p. 263-269 7 p.

Research output: Research - peer-reviewArticle

Mitochondrial Genome
Nucleic Acid Databases
Cypriniformes
Transfer RNA
Documentation
9 Citations

Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats

Kamisan, F. H., Yahya, F., Mamat, S. S., Kamarolzaman, M. F. F., Mohtarrudin, N., Kek, T. L., Salleh, M. Z., Hussain, M. K. & Zakaria, Z. A. Apr 4 2014 In : BMC Complementary and Alternative Medicine. 14, 123

Research output: Research - peer-reviewArticle

Carbon Tetrachloride
Methanol
Liver
Wounds and Injuries
Superoxides
1 Citations
Norepinephrine Plasma Membrane Transport Proteins
Serotonin Plasma Membrane Transport Proteins
Somatoform Disorders
Depression
Therapeutics

Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients

Bannur, Z., Salleh, M. Z., Hashim, H., Hennessy, T., Azmi, M. N., Zailani, M. H., Ramasamy, P., Zakaria, Z. A., Suneet, S., Ngow, H., Henry, G. & Teh, L. K. 2014 In : International Journal of Pharmacy and Pharmaceutical Sciences. 6, SUPPL. 2, p. 288-295 8 p.

Research output: Research - peer-reviewArticle

Metabolomics
Pharmacogenetics
Fluorouracil
Colorectal Neoplasms
Healthy Volunteers
4 Citations

Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations

Mahmood, N. D., Nasir, N. L. M., Rofiee, M. S., Tohid, S. F. M., Ching, S. M., Teh, L. K., Salleh, M. Z. & Zakaria, Z. A. Dec 1 2014 In : Pharmaceutical Biology. 52, 12, p. 1598-1623 26 p.

Research output: Research - peer-reviewArticle

Pharmacology
Search Engine
Phytochemicals
Elaeocarpaceae
Hope
6 Citations
Pharmacogenetics
Malaysia
Delivery of Health Care
Pharmacists
Physicians
2 Citations

Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients

Hamzah, S., Teh, L. K., Siew, J. S. K., Ahmad, G., Wong, H. S., Zakaria, Z. A. & Salleh, M. Z. Jan 2014 In : Canadian Journal of Physiology and Pharmacology. 92, 1, p. 50-57 8 p.

Research output: Research - peer-reviewArticle

Cytochrome P-450 CYP3A
Tacrolimus
Transplants
Kidney
Genotype

Phytochemical screening and In-Silico investigation of 2-benzoxazolinone from Acanthus llicifolius Linn. As dual inhibitors of cyclooxygenase-2 and 5- lipooxygenase enzymes

Saranya, A. R., Manikandan, S., Ramanathan, T., Kesavanarayanan, K. S., Teh, L. K. & Salleh, M. Z. 2014 In : International Journal of Phytomedicine. 6, 3, p. 455-463 9 p.

Research output: Research - peer-reviewArticle

Acanthaceae
Cyclooxygenase 2 Inhibitors
Phytochemicals
Computer Simulation
Ligands
2 Citations

Rapid spectrophotometric determination, characterization and anti-inflammatory efficacy evaluation of nanoencapsulated diclofenac sodium

Goh, J. Z., Chiong, H. S., Zuraini, A., Arifah, A. K., Zakaria, Z. A., Teh, L. K., Salleh, M. Z. & Nazrul Hakim, M. 2014 In : Journal of Drug Delivery Science and Technology. 24, 4, p. 361-366 6 p.

Research output: Research - peer-reviewArticle

Diclofenac
Anti-Inflammatory Agents
Liposomes
Histamine
Edema
mu Opioid Receptor
Drug Users
Single Nucleotide Polymorphism
High Pressure Liquid Chromatography
Personality
7 Citations

The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach

Bannur, Z., Teh, L. K., Hennesy, T., Rosli, W. R. W., Mohamad, N., Nasir, A., Ankathil, R., Zakaria, Z. A., Baba, A. & Salleh, M. Z. 2014 In : Clinical Biochemistry. 47, 6, p. 427-431 5 p.

Research output: Research - peer-reviewArticle

6-Mercaptopurine
Metabolomics
Metabolites
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Therapeutics
2013
11 Citations
Pain Measurement
Methanol
Morphine
Aspirin
Peptamen
2 Citations
Constriction
Glutamic Acid
naltrindole
Methylene Blue
Capsaicin
1 Citations

Draft genome sequence of a clinical isolate of Mycobacterium tuberculosis strain PR05

Ismail, A., Teh, L. K., Ngeow, Y. F., Norazmi, M. N., Zainul, Z. F., Tang, T. H., Najimudin, N. & Salleh, M. Z. 2013 In : Genome Announcements. 1, 3, e00397-13

Research output: Research - peer-reviewArticle

Mycobacterium tuberculosis
Cerebrospinal Fluid
Tuberculosis
Genome

Draft genome sequence of Klebsiella pneumoniae isolate PR04

Zulkifli, M. H., Teh, L. K., Lee, L. S., Zakaria, Z. A. & Salleh, M. Z. 2013 In : Genome Announcements. 1, 4, e00418-13

Research output: Research - peer-reviewArticle

Klebsiella pneumoniae
Genome
Malaysia

Draft genome sequence of Streptococcus agalactiae PR06

Irma Syakina, M. Z., Teh, L. K. & Salleh, M. Z. 2013 In : Genome Announcements. 1, 3, e00351-13

Research output: Research - peer-reviewArticle

Streptococcus agalactiae
Genome
Bovine Mastitis
Gram-Positive Bacteria
Streptococcus
6 Citations

Effects of the total alkaloidal extract of Murraya koenigii leaf on oxidative stress and cholinergic transmission in aged mice

Mani, V., Ramasamy, K., Ahmad, A., Wahab, S. N., Jaafar, S. M., Kek, T. L., Salleh, M. Z. & Majeed, A. B. A. Jan 2013 In : Phytotherapy Research. 27, 1, p. 46-53 8 p.

Research output: Research - peer-reviewArticle

Murraya
Cholinergic Agents
Alzheimer Disease
Oxidative Stress
Brain
3 Citations

Genome sequence of Proteus mirabilis strain PR03, isolated from a local hospital in Malaysia

Khalid, M. I. H., Teh, L. K., Lee, L. S., Zakaria, Z. A. & Salleh, M. Z. 2013 In : Genome Announcements. 1, 3, e00327-13

Research output: Research - peer-reviewArticle

Proteus mirabilis
Malaysia
Genome
Base Composition
Urinary Tract Infections
10 Citations

Hepatoprotective activity of methanolic extract of bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats

Yahya, F., Mamat, S. S., Kamarolzaman, M. F. F., Seyedan, A. A., Jakius, K. F., Mahmood, N. D., Shahril, M. S., Suhaili, Z., Mohtarrudin, N., Susanti, D., Somchit, M. N., Teh, L. K., Salleh, M. Z. & Zakaria, Z. A. 2013 In : Evidence-based Complementary and Alternative Medicine. 2013, 636580

Research output: Research - peer-reviewArticle

Bauhinia
Acetaminophen
Methanol
Liver
Silymarin